evaluation of cytotoxic effects of some novel tetralin derivatives against human cancer cells
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Synthesis and Cytotoxic Evaluation of Some Novel Sulfonamide Derivatives Against a Few Human Cancer Cells
Sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. In addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the G1 phase, disruption of microtubule assembly, suppression of the transcription activator Nf-Y, angiogenesis and matrix metalloproteinase (MMP). In recent years, novel...
متن کاملSynthesis and Cytotoxic Evaluation of Some Novel Sulfonamide Derivatives Against a Few Human Cancer Cells
Sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. In addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the G1 phase, disruption of microtubule assembly, suppression of the transcription activator Nf-Y, angiogenesis and matrix metalloproteinase (MMP). In recent years, novel...
متن کاملsynthesis and cytotoxic evaluation of some novel sulfonamide derivatives against a few human cancer cells
sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. in addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation in the g1 phase, disruption of microtubule assembly, suppression of the transcription activator nf-y, angiogenesis and matrix metalloproteinase (mmp). in recent years, novel...
متن کاملAssessment of the Cytotoxic Effect of a Series of 1,4-Dihydropyridine Derivatives Against Human Cancer Cells
Cancer is a leading cause of death worldwide. Despite the availability of several chemotherapeutic drugs, there is still a great need for more efficient agents for a better management of cancer. In this contribution, a series of 11 DHPs (4a, 4b & 7a-i) were synthesized and evaluated for their cytotoxic effect against MCF-7, LS180, and MOLT-4 cancer cell lines using MTT assay. Synthesized 2,6-di...
متن کاملAssessment of the Cytotoxic Effect of a Series of 1,4-Dihydropyridine Derivatives Against Human Cancer Cells
Cancer is a leading cause of death worldwide. Despite the availability of several chemotherapeutic drugs, there is still a great need for more efficient agents for a better management of cancer. In this contribution, a series of 11 DHPs (4a, 4b & 7a-i) were synthesized and evaluated for their cytotoxic effect against MCF-7, LS180, and MOLT-4 cancer cell lines using MTT assay. Synthesized 2,6-di...
متن کاملassessment of the cytotoxic effect of a series of 1,4-dihydropyridine derivatives against human cancer cells
cancer is a leading cause of death worldwide. despite the availability of several chemotherapeutic drugs, there is still a great need for more efficient agents for a better management of cancer. in this contribution, a series of 11 dhps (4a, 4b & 7a-i) were synthesized and evaluated for their cytotoxic effect against mcf-7, ls180, and molt-4 cancer cell lines using mtt assay. synthesized 2,6-di...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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